Nightfall Dome

Main
This is where SMO kept Mike at bay, figuring its dome is too hard for him. After meeting two other carriers of the blood type: E, they worked together to fight off the. While doing so they accidentally blew up the top of the dome,resulting if the spread of the plague(see episode:Infestation)

Geography
Nightfall City is basically Manhattan. Due to SMO's experiments, they accidentally unleashed a new strain of virus called Necronites. it spreads throughout the air causing the host to a Necromorphosis which reassembles their genes causing deformation of organs and/or organelles of the host.

Nightfall City's official name is The Twilight Zone.